Mecobalamin is one of the active coenzymes of vitamin B12. As a coenzyme of methionine synthase, it participates in the biochemical reaction of homocysteine demethylation to methionine and plays a key role in the process of methylation transfer.

1、 Drug name

Methylcobalamin tablets, commonly known as Mecobalamin.

2、 Indications

Used for treating peripheral neuropathy (peripheral neuropathy).

3、 Specifications and characteristics

The 500 μ g tablet is a white sugar coated tablet with a diameter of 7.3mm, a mass of 155mg, and a thickness of 4.0mm.

4、 Main components

The active ingredient is methylcobalamin.

5、 Usage and dosage

1. The standard adult dosage is 1500 μ g of mecobalamin per day, taken orally in three doses.

2. 500 μ g tablets: 1 tablet each time, 3 times a day.

3. It can be adjusted appropriately according to age and symptoms.

6、 Dose adjustment

Children have not undergone clinical trials and lack recommended doses.

7、 Medication precautions

1. Not explicitly required to be taken before or after meals.

2. PTP packaged drugs should be instructed to be taken by patients after being removed from the PTP board to prevent accidental ingestion that may cause damage or even perforation of the esophageal mucosa.

3. If there is no therapeutic effect after taking it for a period of time, it should not be used aimlessly for a long time.

8、 Medication for special populations

1. Children: No clinical trials have been conducted, lacking safety and efficacy data.

2. Occupational exposure to mercury and its compounds: Long term and large doses should be avoided.

9、 Adverse reactions

1. The incidence rate is below 0.1% to 5%: loss of appetite, nausea, vomiting, and diarrhea.

2. Occurrence rate below 0.1%: rash (allergic reaction).

10、 Contraindications

Absolute contraindications are not explicitly listed.

11、 Drug interactions

Unclear drug interactions.

12、 Storage method

1. Store at room temperature (away from light and moisture).

2. The validity period is 3 years.

3. PTP tablets: Store away from light and moisture (light can reduce the content, while moisture can turn the tablets red).

4. Bottles or aluminum bags should also be kept away from light and moisture after opening.

13、 Manufacturer

Manufacturer and seller: Eisai Co., Ltd

Methycobalinformation