The usage and dosage of Upatinib should be adjusted according to the patient's age, indications, and individual situation. It is usually taken orally once a day, and the specific dosage should follow the doctor's advice. The following provides detailed explanations on standard dosage, adjustments for special populations, and precautions. 1. Standard dose (1) for adult patients: The recommended dose is 15mg or 30mg orally once daily, and the specific dose needs to be determined according to the indications (such as rheumatoid arthritis, psoriatic arthritis, etc.) and the severity of the condition . (2) Pediatric patients: Currently, there is no clear recommended dosage for children, and individualized adjustments should be made under the guidance of a doctor. 2. Dose adjustment for special populations (1) Liver function impairment: Mild or moderate impairment does not require dose adjustment; Severely injured individuals should avoid or reduce their use . (2) Renal function impairment: Mild to moderate impairment does not require adjustment; Severely injured individuals should use with caution and monitor for adverse reactions . (3) Elderly patients: usually do not require adjustment, but closely monitor drug tolerance. 3 precautions (1) It can be taken on an empty stomach or after a meal, but it is necessary to take the medication at a fixed time to maintain stable blood drug concentration . (2) If missed once, it should be taken as soon as possible when remembered, but if it is close to the next medication time, it should be skipped and double the dose should not be taken. (3) During the treatment period, it is necessary to regularly monitor indicators such as signs of infection, liver function, and blood routine.