Ivermectin cream is mainly used to treat skin diseases such as scabies and rosacea. Its common side effects include local irritation reactions, most of which are mild and self relieving. The following are the specific classification of side effects and corresponding relief methods of the drug, which need to be taken in conjunction with clinical reactions to take targeted measures.

1. Common side effects and mitigation methods

(1) Local skin reaction

There may be a burning sensation, itching, or redness, usually temporary. It is recommended to use cold compress to relieve symptoms and avoid scratching the affected area. If it lasts for more than 48 hours, medication should be suspended and a doctor should be consulted.

(2) Dry and desquamation

Medications may cause dryness or slight peeling of the skin. Fragrance free moisturizers can be used during the medication interval, but it is necessary to ensure that there is a gap of at least 2 hours between the application of ivermectin.

2. Serious side effects to be wary of

(1) Allergic reactions

In rare cases, urticaria, facial swelling, or difficulty breathing may occur. Immediate discontinuation of medication and medical attention is required, and antihistamines or adrenaline may be used for treatment if necessary.

(2) Secondary infection

If there is pus and persistent fever at the medication site, it may indicate bacterial infection. Pathogen testing and combined antibiotic treatment are required.

3. Precautions for special populations

(1) Children's use

Safety data for children under 2 years old is limited and strict adherence to medical advice is required. Avoid drug contact with eyes or mouth, and use physical barriers for protection if necessary.

(2) Pregnant women

Animal experiments have shown potential risks, and the benefit risk ratio should be fully evaluated for use during pregnancy. During lactation, avoid applying to the chest area.

4. Drug interaction prevention

(1) Other external medications

Avoid using skincare products containing alcohol or acidic ingredients at the same time, as it may enhance irritation reactions. It is recommended to use different formulations at intervals of at least 1 hour.

(2) Systemic medication

Combined use with CYP3A4 inhibitors may increase the risk of systemic absorption and require monitoring for neurological side effects such as dizziness or tremors.