Lima Prostaglandin Tablets are a novel prostaglandin E1 derivative primarily used to improve subjective symptoms in patients with degenerative lumbar spinal stenosis, such as lower back and lower limb pain and numbness.

1、 Drug name

Common name: Limaprost tablets

2、 Indications

Mainly used to treat the following symptoms caused by lumbar spinal stenosis:

Improve symptoms such as numbness, pain, and intermittent claudication.

Improve subjective symptoms (such as lower limb soreness, numbness, and coldness) and mobility.

3、 Specifications and characteristics

Specification: Each tablet contains limaprost alpha tablets equivalent to 5 μ g of limaprost.

Appearance: This product is a white tablet.

4、 Main components

Active ingredient: limaprost alpha tablets.

5、 Usage and dosage

Conventional dose: Typically, adults take one tablet orally in three doses per day (i.e. a total daily dose of 15 μ g of limaprost).

Usage: Take after meals.

6、 Medication precautions

Before and after meals: It is recommended to take it after meals.

Handling of missed doses: If missed once, it should be replenished as soon as possible when remembered. If it is close to the next medication time, skip the missed dose and take the next dose at the regular time. Do not take double the dose at once.

Vomiting treatment: If vomiting occurs after taking medication, additional medication should not be taken, and medication should be taken normally at the scheduled time.

General precautions:

This drug is a chemically unstable hydroperoxide, and should be used as soon as possible after opening, avoiding light and high temperatures.

Prohibited for individuals allergic to prostaglandin drugs.

7、 Medication for special populations

Pregnant and lactating women: Safety has not been established yet, and should be used after weighing the pros and cons.

Children: Safety has not yet been established.

Elderly people: usually with reduced physiological function, attention should be paid to observing the patient's condition and administering medication with caution.

Individuals with liver and kidney dysfunction: Use with caution in those with severe liver and kidney dysfunction.

8、 Adverse reactions

This product may cause the following adverse reactions (incidence unknown):

Serious adverse reactions:

Shock and allergic reactions: Blood pressure drop, difficulty breathing, urticaria, facial edema, etc. may occur. Once they occur, medication should be stopped immediately and appropriate treatment should be taken.

Liver function impairment and jaundice: Elevated levels of AST (GOT), ALT (GPT), and γ - GTP may occur, and liver function should be checked regularly.

Gastrointestinal bleeding: gastric and duodenal ulcers, bleeding, etc. may occur.

Interstitial pneumonia: may cause fever, cough, difficulty breathing, etc. Once it occurs, medication should be stopped and treatment with corticosteroids should be given.

Other common adverse reactions:

Digestive system: diarrhea, nausea, vomiting, abdominal pain, stomach discomfort, loss of appetite, etc.

Skin: rash, itching.

Mental nervous system: headache, dizziness.

Liver: Abnormal liver function.

Other: facial flushing, fever, palpitations.

9、 Contraindications

Patients with a history of allergies to the ingredients of this medication.

Pregnant or potentially pregnant women.

10、 Drug interactions

Attention should be paid when combining with the following drugs:

Anticoagulants (such as warfarin): may enhance anticoagulant effects, increase bleeding risk, and require close monitoring of coagulation function.

Antiplatelet drugs (such as aspirin): may increase the risk of bleeding.

Non steroidal anti-inflammatory drugs (NSAIDs): may weaken the efficacy of this drug and increase gastrointestinal side effects.

Other prostaglandin drugs: may enhance pharmacological effects or side effects.

11、 Storage method

Storage conditions: Sealed, away from light, stored at room temperature (1-30 ° C).

Attention: Please keep out of reach of children.

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