Testosterone undecylate capsules are a prescription drug that belongs to exogenous androgen drug preparations.

1、 Drug name

Common name: Testosterone undecylate capsules

Product Name: Andriol ® (AndriolTestocaps)‌

2、 Indications

This medicine is used for testosterone replacement therapy in adult males to treat conditions related to endogenous testosterone deficiency or absence.

Testosterone deficiency must be confirmed through clinical features and two independent and effective biochemical tests (morning testosterone) before treatment can begin.

3、 Specifications and characteristics

Specification: Each capsule contains 40 milligrams of testosterone undecylate.

4、 Main components

Active ingredient: Testosterone undecanoate.

Non active ingredients: castor oil, gelatin, glycerol, propylene glycol monolaurate, and sunset yellow (E110, FD&C Yellowno. 6).

5、 Usage and dosage

Recommended dosage: The initial treatment is usually 120-160 milligrams per day, taken in two doses (once in the morning and once in the evening), lasting for 2-3 weeks. The subsequent maintenance dose (40-120 milligrams per day) should be adjusted based on the subsequent testosterone levels and/or clinical effects obtained during treatment.

Usage: To ensure full absorption, it must be taken with meals and swallowed whole. Do not chew.

6、 Dose adjustment and special case handling

Missed dose: If one dose is missed, the regular dose should be taken at the next scheduled medication time, and double the dose should not be taken.

Vomiting: If vomiting occurs shortly after taking medication, it should not be taken immediately as the amount of medication absorbed cannot be determined. You should wait until the next scheduled medication time to take the regular dose.

Dosage: As mentioned earlier, it must be taken with food. Fat helps with its absorption.

7、 Medication for special populations

Children (<18 years old): Not suitable for children under 18 years old, as the safety and efficacy in this patient population have not been determined. If used to stimulate adolescent development, caution should be exercised and bone maturity should be closely monitored.

Elderly people (>65 years old): Clinical data for this population is limited, and there is insufficient support for long-term efficacy and safety. The impact on prostate and cardiovascular events is unknown, and caution should be exercised when using it.

Pregnant and lactating women: prohibited. Testosterone may cause harm to the fetus.

Patients with liver dysfunction: It is recommended to regularly monitor liver function. Patients with severe liver disease should use it with caution.

Patients with renal insufficiency: Those with heart and kidney diseases may experience serious complications due to edema (with or without congestive heart failure), and caution should be exercised when using it.

Cardiovascular risk patients: Testosterone may increase blood pressure, and patients with a history of cardiovascular events or risk factors (such as hypertension, ischemic heart disease) should be evaluated before treatment and closely monitored during treatment.

8、 Adverse reactions

Common and significant adverse reactions include: polycythemia (increased hemoglobin, hematocrit, red blood cell count), elevated prostate-specific antigen (PSA), benign prostatic hyperplasia, hypertension, edema, emotional disorders (aggression, depression, anxiety), headache, dizziness, acne, hair loss, weight gain, abnormal liver function tests, abnormal blood lipids, changes in blood glucose tolerance, male breast development, abnormal penile erection, altered libido, testicular atrophy, oligospermia, etc.

Serious adverse reactions: may increase the risk of serious cardiovascular events such as myocardial infarction, stroke, deep vein thrombosis, pulmonary embolism, etc. In addition, there have been reports of liver tumors, severe allergic reactions, and hypercalcemia.

9、 Contraindications

Individuals who are known to be allergic to any of the ingredients in this product are prohibited from using it.

It is forbidden for men who are known or suspected to have prostate cancer or breast cancer.

This product is not suitable for women, and is particularly dangerous for pregnant and lactating women.

There are contraindications to drug interactions.

10、 Drug interactions

Insulin: May lower blood sugar, thereby reducing insulin demand. Diabetes patients need to closely monitor blood glucose and adjust the dosage of hypoglycemic drugs.

Oral anticoagulants (such as warfarin): may enhance anticoagulant effects and require a reduction in anticoagulant dosage.

Corticosteroids or adrenocorticotropic hormones (ACTH): may worsen edema, and patients with concomitant heart, kidney, or liver diseases should be cautious when using them in combination.

Cyclosporine: Testosterone treatment may enhance the effect of cyclosporine and increase the risk of nephrotoxicity.

Food: Must be taken with food to promote absorption.

Herbs: Some herbal products, such as St. John's wort, may interfere with steroid metabolism, thereby reducing plasma testosterone levels.

Laboratory examination: May reduce thyroid hormone binding globulin levels, leading to a decrease in total T4 serum levels.

11、 Storage method

Store in an environment of 15-30 ° C.

Avoid light and moisture.

Do not refrigerate.

Store the blister board in the outer cardboard box.

Please keep out of reach of children.

Andriol Testocapsinformation