The side effects of Aprilast involve various aspects such as the digestive system, nervous system, and skin. Most symptoms can be relieved on their own, but serious adverse reactions should be noted. The following is an explanation from three aspects: common side effects, serious reactions that require medical attention, and corresponding mitigation measures.

1. Common side effects and mitigation methods

(1) Diarrhea: It is recommended to drink small amounts of water multiple times to supplement electrolytes and avoid high-fat diets. If it persists for more than 48 hours or accompanied by dehydration symptoms, seek medical attention.

(2) Headache: It can be relieved by rest, cold compress on the forehead, and if necessary, use acetaminophen to avoid caffeine containing drugs.

(3) Nausea: Taking medication with meals, chewing ginger slices or drinking mint tea can help alleviate symptoms.

2. Serious side effects requiring immediate medical attention

(1) Allergic reactions, such as facial/throat swelling, difficulty breathing, etc., require immediate discontinuation of medication and emergency treatment.

(2) Depression or suicidal tendencies: When experiencing low mood or abnormal behavior, one should immediately report to a doctor.

(3) Severe infection: Persistent fever, cough, or wound failure may indicate immune suppression and require anti infective treatment.

3. Special protective measures

(1) Weight monitoring: Record weight every week, and assess nutritional status if there is an unexplained decrease of more than 5%.

(2) Skin care: Avoid scratching when rash appears, use non irritating moisturizers, and strengthen sun protection under sunlight.

(3) Drug interactions: Avoid using CYP450 inducers (such as carbamazepine) in combination, as it may reduce drug efficacy.