The storage of Clofazimine should pay attention to temperature control and avoid light, and the medication plan should be adjusted according to the characteristics of special populations. The following is a detailed explanation of specific storage requirements and medication precautions:

1. Basic storage conditions

(1) Temperature: It is recommended to store the original packaging sealed below 25 ℃, and it can withstand short-term temperature fluctuations of 15-30 ℃.

(2) Lighting: It should be strictly stored in the dark, avoiding direct sunlight or strong artificial light sources.

(3) Humidity: Maintain a dry environment to prevent drugs from getting damp and deteriorating. Use immediately after opening.

2. Differences in storage of different dosage forms

(1) Capsules: should always be stored in the original container, ensuring the lid is tightly closed to prevent moisture absorption.

(2) Tablets: The original packaging aluminum foil should be retained and resealed to prevent oxidation after each use.

(3) Suspension: After preparation, the opening date should be marked, and it should be refrigerated at 2-8 ℃ for no more than 7 days.

3. Special precautions

(1) Do not freeze: All dosage forms cannot be frozen, as low temperatures can cause structural damage to the drug.

(2) Child safety: Store in a locked medicine cabinet or high place to prevent children from accidentally taking it.

(3) Expired disposal: Expired drugs need to be recycled according to the hazardous drug disposal regulations.

4. Medication precautions

4.1 Medication for special populations

(1) Pregnant women: Animal experiments have shown embryotoxicity and should only be used when the benefits significantly outweigh the risks.

(2) Breastfeeding period: Medication can be secreted into breast milk, it is recommended to suspend breastfeeding during treatment.

(3) Children: Lack of data for children under 5 years old, dosage needs to be accurately calculated based on weight.

(4) Elderly individuals are more prone to gastrointestinal reactions. It is recommended to administer medication in divided doses and monitor liver function.

4.2 Liver and kidney function adjustment

(1) Liver dysfunction: Moderate damage should be reduced by 50%, and severe damage should be avoided.

(2) Renal insufficiency: Mild to moderate without adjustment, blood drug concentration needs to be monitored in the end-stage.

4.3 Other precautions

(1) G6PD deficiency may induce hemolysis and should be used with caution.

(2) Patients with a history of intestinal obstruction should not use it, as it may worsen abdominal symptoms.

(3) It is recommended to regularly monitor the degree of skin pigmentation during treatment.