Nausea, diarrhea, and headache related to letemovir can mostly be effectively controlled through taking medication with meals, adjusting diet, and symptomatic medication. If the symptoms continue to worsen or affect normal life, it is necessary to contact a doctor in a timely manner, adjust the medication plan, and do not stop taking the medication on your own.

1、 Disgusting coping strategies

1.1 Medication method adjustment

Take it with meals and pad the stomach with light food (such as rice porridge and bread) to avoid fasting irritation.

If the capsule is too large to swallow, you can consult a doctor to see if it should be replaced with an oral suspension.

1.2 Dietary adjustments

Eat small, multiple meals, 5-6 times a day, avoiding greasy, spicy, or overly sweet foods.

Maintain a sitting position for 30 minutes after meals and do not immediately lie down.

You can try taking ginger candy or drinking light ginger tea to relieve nausea.

1.3 Auxiliary measures

If nausea persists, antiemetic drugs (such as ondansetron) can be used under the guidance of a doctor.

Maintain indoor ventilation and avoid irritating odors such as oil fumes.

2、 Self management of diarrhea

2.1 Dietary Adjustment

For the time being, choose low fiber and digestible foods, such as porridge, bananas, applesauce and toast.

Avoid high-fat, dairy products, caffeine, and artificial sweeteners to reduce intestinal irritation.

Increase water intake, but it is advisable to take small sips multiple times and avoid drinking large amounts of water at once.

2.2 Medication Assistance

If diarrhea persists, antidiarrheal medication (such as loperamide) can be used according to medical advice. Take 2 pills for the first time and 1 pill after each bowel movement, with no more than 8 pills per day.

Pay attention to supplementing oral rehydration salts to prevent dehydration and electrolyte imbalance.

2.3 Skin Care

After defecation, gently clean the perianal area with warm water and apply buttock cream or Vaseline to prevent skin damage.

3、 Methods for relieving headaches

3.1 Non pharmacological measures

Ensure sufficient sleep and regular schedule, avoid staying up late.

Resting in a quiet and dimly lit environment, you can apply a cold towel to your forehead or lightly press your temples.

Record the time and cause of headache occurrence to facilitate the investigation of whether it is related to medication time.

3.2 Drug intervention

If headaches affect daily life, acetaminophen (paracetamol) can be used under the guidance of a doctor to relieve them.

Avoid using nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin, as they may increase the risk of bleeding (especially when platelet count is low).