Prussian Blue is used for promoting the elimination of thallium or radioactive cesium in the body, but it is not suitable for everyone. Clarifying the contraindicated population is the primary prerequisite for safe medication, especially focusing on the two core risks of intestinal obstruction and allergy history.

1. Absolutely prohibited population

1.1 Patients with intestinal obstruction or severe intestinal motility disorders

Individuals with complete or incomplete intestinal obstruction, paralytic intestinal obstruction, severe constipation, or significantly reduced intestinal peristalsis are prohibited from taking Prussian blue. This drug requires complete intestinal peristalsis to bind with thallium or cesium and be excreted with feces. If the intestines are not unobstructed, drugs cannot be effectively excreted, which may worsen obstruction and even trigger acute abdominal diseases such as intestinal perforation or intestinal wall ischemia.

1.2 Individuals allergic to any ingredient of this product

Those who are known to be allergic to Prussian blue (ferrocyanide) or its excipients are prohibited from using it. Allergic reactions can manifest as rash, urticaria, facial or laryngeal edema, difficulty breathing, etc. Those who have experienced the above symptoms after taking this product in the past should not use it again.

2. Special circumstances that require careful evaluation

2.1 Severe constipation or difficulty in defecation

Even if the diagnostic criteria for intestinal obstruction are not met, long-term constipation, dependence on laxatives for defecation, or significant reduction in recent bowel movements should be used with caution. Before taking medication, it is necessary to correct constipation and ensure intestinal patency before considering treatment.

2.2 Individuals with a history of intestinal surgery

Patients who have undergone small intestine or colon resection, stoma surgery, etc. may experience changes in intestinal structure and peristaltic function. Before use, it should be thoroughly evaluated by a specialist physician to confirm that the medication can pass and be excreted smoothly.

3. Screening that must be completed before medication

3.1 Detailed Medical History Inquiry

Before taking medication, it is necessary to clearly inquire about:

Whether there are symptoms related to intestinal obstruction such as abdominal pain, bloating, and cessation of bowel movements;

Do you have a history of drug allergies, especially if you have been in contact with Prussian blue or similar blue pigment preparations in the past.

3.2 Abdominal Physical Examination

If intestinal obstruction is suspected, abdominal auscultation, percussion, and palpation should be performed. If necessary, abdominal standing plain film or CT examination should be performed to rule out mechanical or dynamic intestinal obstruction.

3.3 Prepare emergency plans

For individuals with intestinal dysfunction but not absolutely contraindicated, emergency plans should be developed, including indications for discontinuation, supportive treatment measures, and emergency contact channels.