All Names: Dienogest、Visanne、地诺孕素、唯散宁
Indications:Suitable for female patients diagnosed with endometriosis, with symptoms such as pelvic pain and dysmenorrhea, and without clear contraindications.
Manufacturer:Bayer heathcare AG, Germany
Customs Clearance Procedure:If the customs requires the package for customs clearance, please pay the customs clearance fee according to the content of EMS SMS and customs regulations.
Denogestrel tablets are mainly used to treat symptoms such as dysmenorrhea and excessive menstruation caused by endometriosis, as well as symptoms such as dysmenorrhea, excessive menstruation, uterine enlargement, anemia caused by adenomyosis.
1、 Drug name
Common name: Denogestrel
Product Name: VISA
2、 Indications
Used to treat endometriosis and alleviate related symptoms such as pelvic pain, menstrual pain, etc.
3、 Specifications and characteristics
Specification: Each tablet contains 2mg of dienogest
Appearance: White to off white round flat tablets, with the letter "B" engraved on one side and no markings on the other side; Lactose monohydrate 63mg/tablet.
4、 Main components
Active ingredient: Denogestrel
5、 Usage and dosage
Starting time: Starting from the first day of the natural cycle (the first day of menstruation)
Usage: Take 1 tablet daily, continuously (without discontinuation period), at a fixed time every day, and require liquid delivery
Continuous medication: Start the next box immediately after taking each box, without interval.
6、 Dose adjustment
Patients with renal insufficiency do not need to adjust the dosage.
Patients with liver dysfunction are prohibited from using it.
7、 Medication precautions
Dietary impact: Avoid drinking grapefruit juice as it may increase blood drug concentration and the risk of side effects.
Omission treatment: Take one tablet immediately upon recollection, and continue taking the medication at the original time the next day without doubling the dosage.
Vomiting/Diarrhea: If it occurs within 3-4 hours after taking the medication, an additional tablet should be taken.
Effects of discontinuation: Symptoms of endometriosis may recur after discontinuation.
8、 Medication for special populations
Pregnant women: Prohibited, pregnancy must be ruled out before medication.
Breastfeeding period: Not recommended, Denogestrel can enter breast milk.
Teenagers (12-18 years old): A doctor needs to evaluate the benefits and bone health risks.
Elderly people (≥ 65 years old): No relevant applicability.
Children: Prohibited for women before menarche.
9、 Adverse reactions
Common: weight gain, low mood, headache, nausea, abdominal pain, acne, back pain, breast discomfort, vaginal bleeding, etc.
Serious warning: If symptoms of thrombosis occur (such as sudden chest pain, difficulty breathing, leg swelling and pain, persistent headache, visual impairment, etc.), stop medication immediately and seek medical attention.
10、 Contraindications
Disabled if the following situations exist:
Venous thrombotic diseases (such as deep vein thrombosis and pulmonary embolism).
Arterial diseases (such as myocardial infarction, stroke).
Diabetes.
Severe liver disease or liver tumor.
Sex hormone dependent tumors (such as breast cancer and genital cancer).
Vaginal bleeding of unknown cause.
Allergic to Denogestrel or any excipients.
11、 Drug interactions
Weakened efficacy: Antiepileptic drugs (carbamazepine, phenytoin), anti tuberculosis drugs (rifampicin), St. John's wort extract.
Increase blood drug concentration: antifungal drug (itraconazole), some antibiotics (erythromycin), antihypertensive drug (diltiazem).
Other: HIV/hepatitis C treatment drugs may affect blood drug concentration.
12、 Storage method
Storage temperature: ≤ 30 ° C.
Safety requirement: Keep out of reach of children.
Disposal: Professional disposal through pharmacies to avoid environmental pollution.
Dienogestinformation