Cospanon tablets are antispasmodic agents mainly used to relieve spasmodic pain caused by liver, gallbladder, pancreas, and urinary tract stones. Its function may improve muscle contraction rhythm by inhibiting the release of calcium ions (IP ∝ and ryanodine receptors) in smooth muscle cells, and its long-term clinical application effect in Japan is clear.

1、 Drug name

1. Common name: Trihydroxyphenylacetone tablets

2. Product Name: Cospanon

3. Chemical composition: Flopropione, chemical name 1- (3,4,5-trihydroxyphenyl) -1-propanone

2、 Indications

Suitable for smooth muscle spasm symptoms caused by the following diseases: gastric motility disorders, stomach discomfort, stomach tension, indigestion, bloating, irritable bowel syndrome, biliary motility disorders, and pain caused by urinary tract stones.

3、 Specifications

The preparation is tablets, 80mg * 100 tablets/box.

4、 Main components

Flulopropanone (chemical name: 1- (3,4,5-trihydroxyphenyl) -1-propanone).

5、 Usage and dosage

1. Adult standard dosage:

25mg tablets: 1-2 tablets per pill, 3 times a day, taken orally after meals.

50mg tablets: 1 tablet each time, 3 times a day, taken orally after meals.

2. Dose adjustment:

The dosage can be adjusted appropriately based on the severity of symptoms and patient response.

Elderly patients or those with liver and kidney dysfunction should use it with caution and reduce the dosage if necessary.

6、 Dose adjustment

1. Patients with liver and kidney dysfunction: It is recommended to reduce the initial dose by half and adjust according to tolerance.

2. Elderly patients: Due to slowed metabolism, it is recommended to start with low doses and gradually adjust.

7、 Medication precautions

1. Before and after meals: It is recommended to take it after meals to reduce gastrointestinal irritation.

2. Missing dose: If missed once, it should be replenished as soon as possible; But if it is close to the next dose, skip the missed dose and take the next dose according to the original plan, do not double the dose.

3. Vomiting: If vomiting occurs after taking medication, it is not recommended to take it again and wait for the next regular medication time.

4. Other precautions:

Avoid co use with alcohol as it may increase central nervous system inhibition.

During medication, avoid driving or operating dangerous machinery as it may cause drowsiness or dizziness.

If there is an allergic reaction (such as rash, difficulty breathing), the medication should be stopped immediately and medical attention should be sought.

8、 Medication for special populations

1. Pregnant women: Safety has not been established and should only be used when potential benefits outweigh risks.

2. Breastfeeding women: Medications may be secreted through breast milk, and breastfeeding should be suspended or avoided during use.

3. Children: Safety and efficacy have not been established yet, and it is not recommended to use it.

4. Elderly people: Use with caution, starting with low doses.

9、 Adverse reactions

1. Common adverse reactions include dizziness, drowsiness, dry mouth, nausea, and diarrhea.

2. Rare adverse reactions include rash, abnormal liver function, and bradycardia.

10、 Contraindications

1. Prohibited for individuals allergic to fluoxetine or any ingredients in the formulation.

2. Patients with severe liver and kidney dysfunction are prohibited from using it.

3. Pregnant and lactating women are prohibited from using it.

4. Prohibited for children.

11、 Drug interactions

1. Combined use with central nervous system inhibitors (such as alcohol, sedatives): may enhance drowsiness and dizziness.

2. Combined use with anticholinergic drugs: may increase side effects such as dry mouth and constipation.

3. Combined use with liver enzyme inducers (such as rifampicin): may reduce the blood concentration of fluoxetine and weaken the therapeutic effect.

12、 Storage method

1. Store below 30 ° C, avoid moisture and light.

2. Keep out of reach of children.

Cospanoninformation