Oxoralen tablets, as photosensitizers, have clear contraindications for individuals who are allergic to the drug ingredients, patients with specific diseases, and individuals with special physiological conditions. The following will provide a detailed list of specific populations and related precautions against the use of this drug.

Taboo population for methoxysarin tablets

1. Individuals with allergies

Patients with a history of allergies to methoxysarin or any excipients in the formulation are prohibited from using it. If allergic reactions such as rash and difficulty breathing occur after the first medication, the medication should be stopped immediately.

2. Patients with photosensitive diseases

Patients with photosensitive diseases such as lupus erythematosus, porphyria, and pigmentary dry skin disease are prohibited from using the medication as it can exacerbate photosensitive reactions and worsen the condition.

3. Patients with skin cancer or precancerous lesions

Individuals with a history of skin cancer or precancerous lesions such as solar keratosis are prohibited from using UV radiation, as it may promote the development of malignant lesions.

4. Patients without crystalline lenses

Patients with congenital absence of crystalline lens or implantation of artificial lens should not use it, as the lack of ultraviolet filtering function can easily lead to retinal damage.

5. Patients with severe liver dysfunction

Patients with severe liver function impairment are prohibited from using it, as a decrease in liver metabolic capacity may lead to drug accumulation and poisoning.

6. Pregnant and lactating women

Pregnant women are prohibited from using it, as animal experiments have shown embryonic toxicity; Breastfeeding should be stopped during the medication period for lactating women to avoid drugs affecting the baby through breast milk.

Children under 12 years old

Children's skin is highly sensitive to ultraviolet radiation, and the safety of the medication has not been established, therefore its use is prohibited.

Relatively contraindicated population (requires careful evaluation)

1. Cardiovascular disease patients

Patients with severe hypertension or coronary heart disease need to weigh their risks, as phototherapy may increase cardiovascular burden.

2. Individuals with low immune function

HIV infected individuals or patients who have been using immunosuppressants for a long time may have an increased risk of skin tumors due to UV irradiation.

3. Elderly patients

Patients over 65 years old should reduce their use as their skin photosensitivity increases and liver and kidney function may decrease.