Lucretinib may cause side effects such as dizziness, bruising, and weight gain during the treatment process. Mastering scientific coping methods can help alleviate discomfort and ensure continuity of treatment.

1、 Coping strategies for dizziness

1. Slowly change position

When standing up from a lying or sitting position, the movement should be slowed down, the support should be stabilized, and walking should be done after adaptation to avoid dizziness or falls caused by orthostatic hypotension.

2. Avoid dehydration

Ensure sufficient drinking water daily and avoid prolonged exposure to high temperatures or excessive sweating after vigorous exercise to prevent insufficient blood volume from exacerbating dizziness.

3. Monitor blood pressure if necessary

If dizziness occurs frequently, it is recommended to have a blood pressure monitor at home, measure and record it regularly, so that doctors can evaluate whether to adjust the dosage.

2、 Protection against bruising and bleeding tendency

1. Avoid collisions and external injuries

Pay attention to protecting limbs in daily activities and avoid vigorous exercise or contact activities. Use a soft bristled toothbrush to brush your teeth and reduce the risk of gum bleeding.

2. Use with caution drugs that affect coagulation

Without the permission of a doctor, non steroidal anti-inflammatory drugs or anticoagulants such as aspirin and ibuprofen should not be taken on their own to avoid exacerbating bleeding tendencies.

3. Skin care

If bruising occurs, apply cold compress locally within 24 hours and switch to hot compress to promote absorption after 24 hours. If the scope of bruising expands or there are unexplained bleeding points, medical attention should be sought promptly.

3、 Management suggestions for weight gain

1. Balanced dietary structure

Properly control the intake of high calorie and high-fat foods, increase the proportion of vegetables, whole grains, and high-quality protein, and avoid excessive weight gain due to increased appetite.

2. Regularly engage in aerobic exercise

Maintaining moderate intensity exercise for over 150 minutes per week, such as brisk walking, swimming, or cycling, can help burn excess calories and improve overall metabolic status.

3. Monitor weight changes

It is recommended to weigh and record the weight at a fixed time every week. If the weight gain is obvious in a short period of time (such as more than 2 kg a week), it is necessary to be alert to water and sodium retention and inform the doctor in time for evaluation.