As a thyroid stimulating hormone releasing hormone analog, there are specific contraindications, dietary restrictions, and medication constraints for its use, which must be strictly followed to avoid serious adverse reactions.

1. Taboo population

(1) Hyperthyroidism patients

Due to the potential stimulation of thyroid hormone secretion by drugs, hyperthyroidism patients should avoid using them to prevent the condition from worsening.

(2) Severe cardiovascular disease patients

Patients with acute myocardial infarction and severe arrhythmia are prohibited from using the medication as it may increase cardiac burden.

(3) Pregnant women

Animal experiments have shown embryonic toxicity, and pregnant women are prohibited from using it; Women of childbearing age need to confirm that they are not pregnant and take contraceptive measures when taking medication.

(4) Children and adolescents

Insufficient safety data for people under 18 years old, not recommended for use.

2. Forbidden foods

(1) Iodine rich foods

Kelp, seaweed, and other substances may interfere with thyroid function testing. It is recommended to limit intake during medication.

(2) Alcoholic beverages

Possible enhancement of central nervous system side effects, alcohol should be avoided during medication.

(3) Caffeine products

Strong tea and coffee may exacerbate cardiovascular reactions such as palpitations. It is recommended to reduce consumption.

3. Restrictive conditions

(1) Patients with liver dysfunction

Dosage adjustment and close monitoring of transaminase are necessary, and patients with severe liver damage should avoid using it.

(2) Individuals with renal insufficiency

When the creatinine clearance rate is less than 30mL/min, a 50% reduction is required, and it is contraindicated for patients with end-stage renal disease.

(3) Patients with neurological disorders

Epilepsy and Parkinson's disease patients should use it with caution as it may worsen tremors or trigger seizures.

(4) Medication time limit

The last dose of medication should be taken no later than 4pm daily to avoid affecting nighttime sleep.