Almogran is a selective 5-HT1B/1D receptor agonist specifically designed for the acute treatment of adult migraine attacks. The use of Almogran requires strict adherence to precautions, with a focus on cardiovascular contraindications, drug interactions, and medication for special populations to ensure safety and efficacy. It relieves migraines by constricting blood vessels, but caution should be taken against adverse reactions such as chest pain.

1 Indications

(1) Acute migraine treatment is suitable for adult migraine attacks with or without premonitory symptoms, which can quickly alleviate typical symptoms such as headache, nausea, photophobia, and fear of sound. It should be taken in the early stages of pain, but it is ineffective in preventing migraines.

2 Cardiovascular Risks

(2) Prohibited for patients with ischemic heart disease, Prinzmetal angina, or uncontrolled hypertension. If cardiovascular symptoms such as chest pain and palpitations occur after medication, the medication should be stopped immediately and medical evaluation should be sought.

3 drug interactions

(3) Do not use in combination with MAO inhibitors (use after 14 days of discontinuation). Avoid co administration with other triptans or ergotamine drugs, as co administration with SSRIs/SNRIs may increase the risk of 5-HT syndrome.

4. Medication for special populations

(4) Use only during pregnancy when the benefits are clear; It is recommended to suspend feeding during lactation. Patients over 65 years old should reduce their dosage, and those with moderate to severe liver and kidney dysfunction should use caution or adjust the dosage accordingly.

5 Adverse Reaction Monitoring

(5) Common drowsiness and dizziness; Rare intestinal ischemia or visual impairment. If there is an allergic reaction (such as rash, difficulty breathing), the medication should be stopped immediately and treated.

6 dose limits

(6) The maximum single dose is 12.5mg and cannot be repeated within 24 hours. Use no more than 3 times a week, excessive use may lead to hypertensive crisis.