PursennidTablets is a commonly used laxative for clearing intestinal constipation in Japan. Its main ingredient is sennid, which exerts a laxative effect by stimulating intestinal peristalsis. The following provides a detailed explanation of the key information of the drug from three aspects: ingredient characteristics, dosage, and efficacy.

1. Main components

(1) Active ingredient: Each tablet contains Sennoside as the main active ingredient, with a standard dose of 12mg/tablet.

(2) Accessory composition: Contains lactose, corn starch and other excipients, the specific ratio may vary slightly depending on different manufacturers.

2. Usage and dosage

(1) Adult dose: Usually take 1-2 tablets orally before bedtime, with an effective time of about 8-12 hours. It is recommended to adjust from the minimum dose.

(2) Special populations: Pregnant and lactating women are prohibited from using it, elderly people need to use half the dosage, and children need to follow medical advice.

(3) Precautions for taking: The entire tablet should be swallowed, avoiding chewing. During the medication period, the daily water intake should not be less than 2000ml.

3. Effect of action

(1) Mechanism of action: Fanxie glycoside stimulates the intestinal wall nerve plexus after being decomposed by colonic bacteria, enhancing intestinal peristalsis and secretion function.

(2) Effective characteristics: Belonging to the category of laxatives, it usually produces soft stool the next morning after medication, without causing severe diarrhea.

(3) Course restriction: Continuous use should not exceed one week, long-term use may lead to electrolyte imbalance and drug dependence.

4. Precautions

(1) Contraindications: It is contraindicated for patients with intestinal obstruction, appendicitis, and severe dehydration. For patients with abdominal pain, it should be used after ruling out organic diseases.

(2) Adverse reactions: Mild abdominal pain, bloating, rare rash and other allergic reactions may occur, and medication should be stopped immediately.

(3) Drug interactions: Combination with diuretics increases the risk of hypokalemia, and combination with digoxin requires monitoring of blood drug concentration.