All Names: Pursennid Tablets、清肠便秘缓下剂、プルゼニド錠、ぷるぜにどじょう
Indications:Adult constipation patients with ineffective dietary adjustments.
Manufacturer:
Customs Clearance Procedure:If the customs requires the package for customs clearance, please pay the customs clearance fee according to the content of EMS SMS and customs regulations.
The laxative for clearing constipation has a high short-term relief effect on chronic constipation, and can quickly improve symptoms such as difficulty in defecation and dry stool. It is especially suitable for temporary bowel dysfunction and situations that require intestinal preparation.
1、 Drug name
1. Product Name: Pursennid Tablets
2. Active ingredient: Sennoside A and B (sennoside A and B, in calcium salt form)
3. Dosage form: Sugar coated tablets
2、 Indications
Constipation syndrome.
3、 Specifications and characteristics
1. Specification: Each tablet contains 12mg of sennoside A · B12mg.
2. Appearance: Sugar coated tablets with yellow dark red color.
4、 Main components
Active ingredient: Prusinide (calcium salt of senoside), 12mg of senoside A and B per tablet.
5、 Usage and dosage
1. Conventional dosage: For adults, take orally once a day before bedtime, with a dosage of 12-24mg (i.e. 1-2 tablets) of sennoside A and B.
2. Dosage: Take before bedtime.
6、 Dose adjustment
1. For severe constipation, the single dose can be increased to 48mg (i.e. 4 tablets).
2. The dosage can be adjusted appropriately according to the patient's age and symptoms.
7、 Medication precautions
1. Long term use: Long term continuous use should be avoided, as it may lead to drug resistance, weakened efficacy, and easy drug dependence.
2. Delivery note: If it is packaged in PTP (aluminum-plastic), it should be taken out of the PTP board before consumption to prevent accidental ingestion and damage to the esophageal mucosa.
8、 Medication for special populations
1. Pregnant women and women who may become pregnant: Use only when the benefits of treatment outweigh the risks. Attention should be paid to the possibility of inducing uterine contractions, which poses a risk of miscarriage and premature birth, and should be avoided in large quantities.
2. Breastfeeding women: After weighing the benefits of treatment and breastfeeding, decide whether to continue breastfeeding or discontinue medication. Although there have been reports indicating that sennoside was not detected in breast milk, there have been reports of diarrhea in lactating infants.
3. Children: Clinical trials have not been conducted yet, and safety has not been established.
4. Elderly people: generally have low physiological function, so attention should be paid when taking medication.
5. Post abdominal surgery patients: Due to the fact that this product can enhance intestinal peristalsis, it may induce abdominal pain and requires special attention.
9、 Adverse reactions
1. More than 5% incidence: abdominal pain.
2. The incidence rate is below 0.1% to 5%: diarrhea, nausea, vomiting, and abdominal sounds.
3. The incidence is unknown: allergic reactions such as rash, hypokalemia, hyponatremia, dehydration, blood pressure drop, abdominal discomfort, colorectal melanosis (long-term continuous medication), elevated ALT, elevated AST, elevated gamma GTP, elevated bilirubin, kidney damage, yellow brown or red urine, fatigue.
10、 Contraindications
1. Individuals with a history of allergies to the ingredients of this medicine or preparations containing sennoside.
2. Suspected acute abdominal syndrome and spastic constipation (due to increased peristalsis, symptoms such as abdominal pain may worsen).
3. Severe constipation (oral laxatives have poor efficacy and may worsen symptoms such as abdominal pain).
4. Individuals with electrolyte imbalance (especially hypokalemia) (diarrhea during heavy medication can cause further loss of electrolytes, exacerbating the condition).
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