Taking Longes: List of Side Effects and Precautions. As a commonly used antihypertensive drug, the management of side effects of Longes should be based on individual differences, and precautions include medication monitoring and lifestyle adjustments. The following system summarizes the adverse reaction spectrum and clinical usage points of the drug to help patients use it safely.

1. Common side effects

(1) Cardiovascular system: Postural hypotension is characterized by dizziness or fainting, and the first medication should be monitored while lying down.

(2) Respiratory system: The incidence of dry cough is up to 20%, which is related to the accumulation of bradykinin and usually resolves after discontinuation of medication.

(3) Digestive system: Nausea and vomiting often occur in the early stages of treatment, and taking medication after meals can alleviate symptoms.

2. Serious reactions that require vigilance

(1) Vascular edema: manifested as swelling of the lips and tongue or difficulty breathing, requiring immediate discontinuation of medication and emergency treatment.

(2) Hyperkalemia: People with renal insufficiency have an increased risk, and regular monitoring of blood potassium levels is crucial.

(3) Deterioration of renal function: Patients with renal artery stenosis may experience acute kidney injury and require dose adjustment.

3. Precautions for special populations

(1) Pregnant women should avoid using contraception: Use during the middle and late stages of pregnancy can cause fetal malformation or death. Women of childbearing age should use contraception.

(2) Elderly people: Reduce the initial dose by half to avoid excessive blood pressure reduction leading to insufficient cerebral perfusion.

(3) Liver and kidney dysfunction: The dosage should be adjusted according to the creatinine clearance rate, and it is contraindicated in severe cases.

4. Drug interactions

(1) Diuretics: Combination therapy may cause first dose hypotension. It is recommended to stop diuretics for 2-3 days.

(2) NSAIDs: Drugs such as ibuprofen can weaken the antihypertensive effect and increase the risk of kidney damage.

(3) Potassium sparing diuretics: Do not use in combination, otherwise it may cause fatal hyperkalemia.

5. Daily management suggestions

(1) Monitoring requirements: Regularly check blood pressure, kidney function, and blood potassium, especially in the early stages of treatment.

(2) Dietary restrictions: Avoid high potassium foods such as bananas and orange juice, and limit sodium intake.

(3) Position management: Wake up slowly to prevent falls caused by positional hypotension.