Gilteritinib is an oral targeted drug used to treat specific types of leukemia. The correct administration method, dosage adjustment, and management of missed doses are the basis for ensuring efficacy and safety. The following are the key operational points.

1、 Basic administration methods

1.1 Frequency and duration of administration: once daily, at a fixed time to maintain a stable blood drug concentration.

1.2 Relationship with eating: It can be taken on an empty stomach or with meals. If gastrointestinal discomfort occurs, it is recommended to take it with meals to alleviate symptoms.

1.3 Medication method: Swallow the whole tablet, do not crush or chew.

2、 Principle of dose adjustment

2.1 Adjustment Basis: Dose adjustment must be based on the doctor's evaluation and cannot be adjusted by oneself.

2.2 Common adjustment situations: If serious adverse reactions occur (such as bone marrow suppression, liver dysfunction, etc.), doctors may suspend medication, reduce dosage, or permanently stop medication.

2.3 Recovery of original dose: After the adverse reactions are relieved, the doctor will guide whether and how to restore to the original therapeutic dose.

3、 Handling methods for missed services

3.1 If the missed dose time is less than 12 hours: take it immediately and take it on time for the next time.

3.2 Missing dose time ≥ 12 hours: Skip the missed dose and take it on time for the next time without doubling.

3.3 Post vomiting treatment: If vomiting occurs immediately after taking the medication, do not take any supplements and follow the original plan to take the next dose.

4、 Other important tips

4.1 Drug Interactions: Inform the doctor of all medications being used (including over-the-counter drugs and health supplements) to avoid affecting their efficacy or increasing toxicity.

4.2 Regular monitoring: During the treatment period, it is necessary to follow the doctor's advice and regularly check blood routine, liver and kidney function, and other indicators.