When taking Rufinamide, taking it with meals, dose titration, and leakage management are key steps to ensure efficacy and safety.

1、 Take with meals

It is recommended to take with meals as food can increase absorption and improve bioavailability.

Maintain a relatively fixed administration method and avoid alternating between fasting and postprandial periods.

Take it twice a day, once in the morning and once in the evening, with as even intervals as possible.

2、 Dose titration

The initial dose should be low and gradually increased to reduce adverse reactions such as drowsiness.

The specific starting amount and dosing rate are determined by the doctor based on age, weight, and concomitant medications.

Usually, the dosage is increased every 2 to 3 days until an effective maintenance dose is reached.

When used in combination with sodium valproate, the titration rate needs to be slowed down as the blood drug concentration may increase.

When used in combination with carbamazepine, phenytoin, and phenobarbital, an increase in dosage may be necessary.

If there is obvious drowsiness, dizziness or ataxia during the dosing period, the dosing should be temporarily suspended and the doctor should be informed.

Do not rapidly increase or overdose on your own.

3、 Handling of missed services

If it is too long before the next medication, you can take it as soon as possible.

If it is close to the next medication time, the missed dose should be skipped and the next dose should be taken according to the original plan.

Do not take double the dose at once to make up for missed doses.

Frequent missed doses may affect epilepsy control, and regular medication should be taken as much as possible.

If there is an increase in seizures after missed medication, seek medical attention promptly.

Other: Discontinuation of medication should be gradually reduced, sudden cessation of medication may trigger epileptic seizures. The above is general popular science information. Please follow the doctor's advice when taking medication and seek medical attention promptly if you experience any discomfort.