Ramelteon is a selective melatonin receptor agonist primarily used to treat insomnia with difficulty falling asleep. Its mechanism of action is unique and it is not listed as a controlled drug. The following will explain the effects and drug interactions from two aspects, providing reference for clinical medication.

1. Effect of action

(1) Indications: Suitable for insomnia characterized by difficulty falling asleep, regulating the sleep wake cycle by activating melatonin MT1 and MT2 receptors.

(2) Dosage form specification: Oral tablets, 8 milligrams per tablet, in a circular light orange yellow film coating, with the "TAK" and "RAM-8" logos printed on the tablet body.

(3) Recommended dosage: Adults should take 8 milligrams within 30 minutes before bedtime, and not exceed 8 milligrams per day. Avoid taking it with high-fat meals or immediately after meals.

2. Drug interactions

(1) Other drug effects: Attention should be paid to the possible interactions that may occur when combined with other drugs, and the specific mechanism should refer to the drug instructions or clinical guidelines.

(2) Alcohol effects: Alcohol may enhance the sedative effect of remifentanil, increase the risk of side effects such as dizziness and drowsiness, and should be avoided for simultaneous use.

3. Precautions

(1) Side effects: Common side effects include dizziness, drowsiness, occasional body pain, taste changes, etc. Severe allergic reactions require immediate medical attention.

(2) Special population: Patients with liver dysfunction should use with caution, and the safety of medication for pregnant women, breastfeeding women, and children is not yet clear.

(3) Storage conditions: Store at 25 ° C, allow for a deviation of 15 ° C to 30 ° C, keep the container sealed and moisture-proof, and have a shelf life of 36 months.