Blujepa, as an antibacterial drug, has specific contraindications, dietary restrictions, and medication constraints when used. The following provides detailed explanations from three dimensions: contraindications, dietary taboos, and special restrictions, which must be strictly followed during clinical use.

Contraindicated population

1. Allergic individuals

It is contraindicated for patients allergic to beta lactam antibiotics. Individuals who have previously experienced hypersensitivity reactions such as rash and angioedema should permanently avoid using it.

2. Special physiological state

Pregnant women are prohibited from using it (animal experiments have shown embryotoxicity). Breastfeeding should be suspended during the medication period for lactating women.

3. Organ dysfunction

Patients with severe liver dysfunction (Child Pugh C grade) are contraindicated. Patients with end-stage renal disease (GFR<15mL/min) need to adjust the dosage.

Taboo foods

1. Alcoholic beverages

During the medication period and within 72 hours after discontinuation, alcohol consumption is prohibited as it may trigger disulfiram like reactions (facial flushing, palpitations, etc.).

2. High calcium foods

Milk, cheese and other dairy products should be taken every 2 hours, and calcium ions can significantly reduce drug absorption by 30% -50%.

3. Iron supplements

Iron supplements form chelates with geboda star, and it is recommended to take them 4 hours apart. Anemic patients need to monitor changes in hemoglobin.

Constraints

1. Course control

The routine infection course should not exceed 14 days. Extended use requires weekly monitoring of liver and kidney function to prevent the accumulation of toxicity.

2. Combination therapy

Do not use in combination with potent diuretics as it increases the risk of nephrotoxicity. Combined use with oral contraceptives requires additional contraceptive measures.

3. Special populations

Elderly patients aged 65 and above need to reduce their dosage by 25%. Patients with a history of epilepsy need to monitor changes in electroencephalogram during medication.