Adverse reactions during treatment are common, and active management can significantly improve quality of life. The following are home treatment strategies for the three core symptoms. Please inform the attending team before any intervention.

1. Diarrhea management (intervene if diarrhea occurs more than 3 times a day)

1.1 Fluid replacement and diet: Oral rehydration salts or diluted fruit juice or clear soup are preferred. Stop dairy products, high fiber and greasy food, and change to low residue diet such as porridge, bananas and toast.

1.2 Medication Assistance: Follow the doctor's advice to prepare Loperamide (4mg for the first dose, 2mg after each bowel movement, with a daily limit of 16mg). If medication is ineffective within 24 hours or if bloody stools or fever occur, emergency medical attention is required.

1.3 Perianal care: After cleaning with warm water, apply a buttock cream to avoid secondary skin damage.

2. Nausea control (prevention is better than treatment)

2.1 Meal adjustment: Change from taking medication with meals to taking it immediately after meals; Eat small meals frequently and avoid foods that are too sweet, too hot, or have strong spicy odors.

2.2 Environment and Smell: Maintain ventilation and smell lemon or peppermint essential oil to alleviate nausea. Half an hour before meals, you can try taking ginger candy or ice lozenges.

2.3 antiemetic medication: If it affects eating, the doctor will prescribe antiemetic drugs such as ondansetron, which should be used preventively 30 minutes before taking the medication.

3. Fatigue coping (continuous fatigue requires proactive management)

3.1 Energy Conservation: Disperse daily activities to the optimal time for energy (such as in the morning), and schedule 10-15 minutes of meditation breaks between each task.

3.2 Mild activity: Take a 5-10 minute walk or stretch your limbs daily, which is more helpful in maintaining muscle strength than completely lying in bed, but avoid excessive exercise.

3.3 Sleep hygiene: Set a fixed bedtime, take a nap of no more than 30 minutes, and avoid prolonged screen time during insomnia at night.

4. Medical red line

Contact a doctor immediately if the following situations occur: diarrhea more than 8 times a day or accompanied by dizziness and anuria; Vomiting resulting in inability to eat or drink water for 24 hours; Exhausted to the point of being unable to get out of bed or breathing rapidly. Please record the daily frequency of symptoms and weight changes for accurate adjustment of support plans during follow-up visits.