During the treatment of erlotinib, it is important to monitor rash, diarrhea, interstitial lung disease, and liver toxicity. Early identification and management are key to ensuring medication safety.

1、 Rash

1. Performance and monitoring

It often appears in the early stages of treatment and presents as an acne like rash.

Commonly seen on the face, chest, and back.

Skin changes should be observed daily during medication.

2. Key points for handling

Strengthen moisturizing and sun protection to avoid squeezing rashes.

Mild to moderate use of ointment prescribed by a doctor for external application.

When severe or accompanied by infection, timely medical attention should be sought, and medication may need to be suspended or reduced.

2、 Diarrhea

1. Performance and monitoring

Diarrhea is one of the common adverse reactions.

Pay attention to the frequency, characteristics, and accompanying symptoms of bowel movements.

If dehydration, fever, or bloody stool occurs, seek medical attention immediately.

2. Key points for handling

Mild to moderate diarrhea can be treated with antidiarrheal medication according to medical advice.

Pay attention to replenishing water and electrolytes.

Severe diarrhea should be treated by suspending medication and seeking medical attention, and adjusting the dosage if necessary.

3、 Interstitial lung disease

1. Performance and monitoring

It can manifest as newly developed or worsening cough, difficulty breathing, and fever.

The onset may be sudden and requires high vigilance.

Respiratory symptoms during medication should be evaluated promptly.

2. Key points for handling

Suspected interstitial lung disease should be immediately discontinued and medical attention sought.

Imaging and other examinations are required to confirm the diagnosis.

After diagnosis, erlotinib should be permanently discontinued and appropriate treatment should be received.

4、 Hepatotoxicity

1. Performance and monitoring

It can manifest as elevated transaminase levels, jaundice, fatigue, and decreased appetite.

Regular monitoring of liver function should be conducted before and during treatment.

Individuals with abnormal liver function need to increase their monitoring frequency.

2. Key points for handling

Mild abnormalities can continue to be treated with medication and closely monitored.

If there are obvious abnormalities, medication should be suspended and the doctor should evaluate whether to reduce or stop the medication.

Severe liver damage symptoms should be permanently discontinued and actively treated.