Erlotinib should be used with special caution in patients with severe liver and kidney dysfunction, pregnancy, and lactation, and should be avoided in some cases.

1、 Severe liver and kidney dysfunction

1. Liver dysfunction

Patients with severe liver function impairment should use with caution or avoid use.

Liver dysfunction can affect drug metabolism and increase the risk of toxicity.

Regular monitoring of liver function should be conducted before medication and during treatment.

If severe liver damage occurs, the medication should be paused or stopped.

2. Renal insufficiency

Patients with severe renal impairment should be carefully evaluated when taking medication.

Currently, there is a lack of sufficient security data.

During medication, renal function changes should be monitored.

If there are obvious abnormalities, seek medical attention promptly and adjust the plan.

2、 Pregnant women

1. Pregnancy risk

Erlotinib may cause harm to the fetus.

Pregnant women should avoid using it unless the benefits outweigh the risks.

Animal studies have shown the presence of embryonic fetal toxicity.

2. Women of childbearing age

Effective contraception should be taken during the treatment period and for a period of time after the last dose.

If pregnancy occurs during treatment, the doctor should be informed immediately.

Do not discontinue or continue medication on your own, it must be evaluated by a doctor.

3、 Breastfeeding patients

1. Breastfeeding risk

It is not yet clear whether erlotinib is secreted into human milk.

May cause serious adverse reactions to nursing infants.

Breastfeeding women should avoid using it.

2. Suggestions for handling

Breastfeeding should be stopped during medication.

If medication is necessary, alternative feeding methods should be discussed with a doctor.

The time to resume breastfeeding after discontinuing medication should be consulted with a doctor.

4、 Other precautions

1. Pre medication evaluation

Before treatment, liver and kidney function, pregnancy status, and other examinations should be completed.

Provide detailed medical history and medication use to the doctor.

2. Monitoring during treatment

Regularly review liver and kidney function.

Pay attention to adverse reactions such as skin and digestive tract.

Seek medical attention promptly if any abnormalities occur.

3. Individualized decision-making

Special populations need to weigh the pros and cons of medication.

Do not increase or decrease the dosage or discontinue the medication on your own.

All adjustments should be made under the guidance of a doctor.