Miebo is a topical ophthalmic formulation, with its active ingredient being perfluorohexane octane, belonging to the class of semi fluorinated alkanes.

1、 Drug name

1. Common name: Perfluorohexyl Octane Eye Drops

2. Product Name: Miebo

2、 Indications

Used to treat the symptoms and signs of dry eye disease.

3、 Specifications and characteristics

1. Specification: 3mL per bottle, containing 100% perfluorohexane octane.

2. Appearance: Aseptic, transparent, colorless liquid.

4、 Main components

1. Active ingredient: Perfluorohexyl Octane (1,1,1,2,2,3,4,5,6,6-tetrafluorotetradecane).

2. Molecular formula: C ₁₄ H ₁₇ F ₁∝, molecular weight: 432.26g/mol.

5、 Usage and dosage

1. Four times a day, one drop each time, apply to the affected eye.

2. Contact lenses should be removed before use and worn at least 30 minutes after medication.

6、 Dose adjustment

Adjust the dosage according to liver function, kidney function, etc. Please follow the doctor's advice for use.

7、 Medication precautions

1. Before/after meals: Unless otherwise specified, use as usual.

2. Missed dose: If missed, it should be replenished as soon as possible. If it is close to the next dose, skip it and do not double the dosage.

3. Vomiting: unspecified.

4. Other: Avoid contact between the bottle mouth and eyes or skin during use to prevent contamination.

8、 Medication for special populations

1. Pregnant women: Without sufficient human research, animal experiments have shown that high doses in rabbits may cause maternal toxicity, miscarriage, and fetal weight loss. The use should be weighed carefully.

2. Breastfeeding period: Lack of human data, the benefits of breastfeeding and the mother's treatment needs should be considered.

3. Children: The safety and efficacy of patients under 18 years old have not been established.

4. Elderly patients: There is no overall difference in safety or effectiveness compared to younger patients.

9、 Adverse reactions

1. The most common eye adverse reaction is blurred vision (with an incidence rate of less than 4%).

2. Some patients may experience conjunctival congestion (1-3%).

3. A small number of patients may experience hypersensitivity reactions.

10、 Contraindications

Patients with a history of hypersensitivity reactions to perfluorohexane are contraindicated.

11、 Storage method

1. Store at 15 ° C to 25 ° C (59 ° F to 77 ° F).

2. After opening the lid, it can be used within the expiration date indicated on the bottle body.

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