As an SGLT2 inhibitor, the side effects of Inpefa mainly involve the urinary and reproductive system, metabolism, and skin reactions, which can be alleviated by adjusting medication or symptomatic treatment.

Common side effects and mitigation methods

1. Urinary system reactions: Polyuria and frequent urination can be relieved by drinking water in portions, with a daily water intake controlled at 1.5-2 liters; Urinary tract infections require an increase in urination frequency, and timely anti infection treatment is necessary when symptoms appear.

2. Infections of the reproductive system: Female patients are advised to keep the external genitalia dry and use pH balanced washes; Men should pay attention to local cleanliness and use antifungal cream when fungal infections occur.

3. Metabolic abnormalities: For mild hypoglycemia, it is recommended to carry candy with you, and those undergoing insulin therapy should regularly monitor their blood sugar levels; People with insufficient blood volume should avoid getting up suddenly.

Serious adverse reaction management

1. Acute pancreatitis: If persistent abdominal pain occurs, medication should be stopped immediately and medical attention sought. During treatment, a high-fat diet should be avoided.

2. Ketoacidosis: When manifested as difficulty breathing, nausea, and vomiting, blood ketones should be immediately tested and emergency treatment should be sought.

3. Renal dysfunction: Regularly monitor eGFR during medication, and adjust dosage or discontinue medication if abnormalities occur.

Preventive measures

1. Pre medication evaluation: Check baseline renal function, blood glucose, and infection risk factors. Elderly patients need to strengthen monitoring.

2. Lifestyle adjustment: Avoid vigorous exercise under dehydration conditions, and pay attention to supplementing electrolytes in summer.

3. Drug interaction management: Avoid combination with diuretics and NSAIDs, and closely monitor when necessary.

Special precautions

1. Humidity control: The relative humidity of the storage environment should be below 60%. In humid areas, it is recommended to use desiccants to avoid changes in drug dissolution caused by moisture absorption.

2. Light avoidance requirements: Although it is not explicitly required to store in the dark, it is recommended to avoid direct sunlight to reduce the potential risk of photodegradation.