Common side effects of Velexbru hydrochloride include increased risk of bleeding and infection, and close monitoring of related symptoms is necessary. The following is a detailed classification of side effects and risk management recommendations.

Classification of common side effects

1. Bleeding related reactions

May cause bleeding tendency, manifested as abnormal bruising, nosebleeds, gum bleeding, etc. In severe cases, gastrointestinal bleeding or intracranial bleeding may occur, and platelet count should be monitored regularly.

2. Increased risk of infection

Reduced white blood cell count may increase the risk of bacterial, viral, or fungal infections, commonly respiratory infections, and in severe cases, systemic infections such as sepsis may occur.

Serious side effects that require immediate medical attention

3. Severe bleeding symptoms

If central nervous system bleeding symptoms such as vomiting blood, black stool, hematuria, persistent headache, or changes in consciousness occur, medication should be stopped immediately and medical attention should be sought.

4. Severe infection symptoms

Continuous high fever (>38.5 ℃), chills, shortness of breath, blurred consciousness and other manifestations of sepsis require emergency medical intervention.

Risk management measures

5. Bleeding prevention

Avoid using anticoagulant drugs, assess bleeding risk before invasive procedures, and use a soft bristled toothbrush to prevent gum bleeding.

6. Infection prevention

Pay attention to personal hygiene, avoid contact with sources of infection, seek medical attention promptly when symptoms of infection such as fever occur, and undergo blood routine testing.

Other common adverse reactions

7. Non hematological toxicity

Including fatigue (32%), diarrhea (28%), rash (26%), etc., usually grade 1-2, which can be relieved through symptomatic treatment.

8. Cardiovascular effects

May cause arrhythmia (such as atrial fibrillation), regular monitoring of electrocardiogram is necessary, especially for patients with a history of heart disease.